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Wednesday, July 29, 2020 | History

2 edition of Doiron Porphyrin Localization and Treatment of Tumors found in the catalog.

Doiron Porphyrin Localization and Treatment of Tumors

DR DOIRON

Doiron Porphyrin Localization and Treatment of Tumors

by DR DOIRON

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Published by John Wiley & Sons Inc .
Written in English

    Subjects:
  • Biochemistry,
  • Clinical & Internal Medicine,
  • Unassigned Title

  • The Physical Object
    FormatHardcover
    Number of Pages908
    ID Numbers
    Open LibraryOL10337611M
    ISBN 100471833592
    ISBN 109780471833598

    Porphyrins. HP was purchased from Porphyrin Products, Logan, UT. HPD was prepared from HP as described previously (), except that the concentration of HP acetates in the hydrolysis step was 40 mg/ higher acetate concentrations, the yield of the tumor-localizing fraction is improved (10, 18).After 15 min, the mixture was diluted with n NaOH, stirred for 15 min Cited by: PDT is approved for several cancer indications and FD has recently been approved for diagnosis of bladder cancer. The photosensitizers used are in most cases based on the porphyrin structure. These photosensitizers generally accumulate in cancer tissues to a higher extent than in the surrounding tissues and their fluorescing properties may be Cited by:

    The Photodynamic Therapy (PDT) Anticancer Activity of a Range of Porphyrin Dimers and Related Compounds Derived from Hematoporphyrin Christopher J. Byrne A, Mathew A. Cooper A, Prudence A. Cowled B C, Robert A. W. Johnstone D, Lorraine Mackenzie C, Lorely V. Marshallsay A, Ian K. Morris A, Craig A. Muldoon A, Mark J. Raftery A, Sek Sau Yin A and A. Cited by: 6.   Doiron DR, Gomer C (eds): Porphyrin localization and treatment of tumors, in Advances in Experimental Medicine and Biology. New York, Plenum Publishing Corp, , vol New York, Plenum Publishing Corp, , vol Cited by:

    System Upgrade on Feb 12th During this period, E-commerce and registration of new users may not be available for up to 12 hours. For online purchase, please visit us by:   Balchum OJ Doiron DR Huth GC: HpD photodynamic therapy for obstructing lung cancer in Doiron DR Gomer CJ (eds): Porphyrin Localization and Treatment of Tumors. New York: Alan R Liss pp – Balchum OJ Doiron DR Huth GC: HpD photodynamic therapy for obstructing lung cancer in Doiron DR Gomer CJ (eds): Porphyrin Localization Cited by:


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Doiron Porphyrin Localization and Treatment of Tumors by DR DOIRON Download PDF EPUB FB2

Porphyrin localization and treatment of tumors: Proceedings of the Clayton Foundation International Symposium on Porphyrin Localization and Treatment in clinical and biological research) on *FREE* shipping on qualifying offers.

Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (K), or click on a page image below to browse page by by: Biochemical Pharmacology.

Vol. 33, No. 9, pp. Printed in Great Britain. ^84 Ï + © Pergamon Press Ltd. COMMENTARY PORPHYRIN Cited by: — A porphyrin mixture derived from hematoporphyrin and termed HPD (hematoporphyrin derivative) is used for localization and therapy of tumors.

Benson RC Jr: The use of Hpd in the Localization and Treatment of Transitional Cell Carcinoma of the Bladder, In: Doiron DR, Gomer CJ (eds). Porphyrin Localization and Treatment of Tumors. New York: Alan R.

Lisa, Inc. Google ScholarCited by: 2. PHTHALOCYANINES AS PHOTOSENSITIZERS IN BIOLOGICAL SYSTEMS AND FOR THE PHOTODYNAMIC THERAPY OF TUMORS. John D. Spikes. Department of Biology University of Utah Salt Lake City UTUSA. Search for more papers by this author. John D.

Spikes. Abstract. Photodynamic therapy (PDT) has attracted attention because it was considered to be a selective form of cancer treatment causing minimal damage to normal tissues. This is not exactly true, because the ratio Doiron Porphyrin Localization and Treatment of Tumors book the photosensitizer concentrations in tumour and surrounding normal tissues is not always much more than by: administrated porphyrins in malignant tumors with also a certain degree of photonecrosis.

Such promising properties of porphyrins were again put in evidence in vivo by Figge and collaborators in with studies with mice containing induced and transplanted tumors; by fluorescence techniques porphyrin localization was observed in each by: Photodynamic Therapy.

Abstract. Photodynamic therapy (PDT) involves the action of light on a photosensitizer retained in malignant or other diseased tissues.

Application to treatment of cancer in man depends upon relative selective retention in the tumor, low systemic toxicity and the ability of the activating light to reach the diseased site.

Gomer CJ, Doiron DR, Dunn S, et al () Examination of action spectrum, dose rate, and mutagenic properties of hematoporphyrin derivative photoradiation therapy.

In: Porphyrin localization and treatment of tumors. Alan R Liss, Inc, New York Google ScholarCited by: 5. Profio and J. Sarniak, “Fluorescence of HpD for tumor detection and dosimetry in photodynamic therapy” in “Porphyrin Localization and Treatment of Tumors”, pp. –, D. Doiron and C. Gomer edsCited by: 1.

Get this from a library. Porphyrin localization and treatment of tumors: proceedings of the Clayton Foundation International Symposium on Porphyrin Localization and Treatment of Tumors, Santa Barbara, California, April[Daniel R Doiron; Charles J Gomer; Clayton Foundation for Research.;].

Prog Clin Biol Res. ; Porphyrin localization and treatment of tumors. Proceedings of the Clayton Foundation International Symposium. Biochimie 70 () ,~ Soci6t6 de Chimie biologique/Elsevier, Paris Research article Tumor localization of newly developed hematoporphyrin (DHP) using a bladder tumor model" a novel hematoporphyrin derivative * Mohamed EL-FARI, M.

ABOU-EL-ZAHAB~, M. GHONEIM2 and E. IBRAHIM2 1Faculty of Science, Chemistry Dept., and:Urology and Nephrology Centre, Cited by: 4. Photodynamic therapy is an experimental form of cancer treatment for solid tumors.

The mechanism of tumor cell destruction involves the disruption of tumor microcirculation, followed by tumor anoxia, and cell death. To date, many clinical applications with various rates of success have been studied.

We are investigating the feasibility of photodynamic therapy in the treatment of localised prostatic cancer. Of major importance in this form of treatment is the extent to which light penetrates the target organ; hence, our interest in the optical properties of the human prostate by: Tumor localization and photosensitization by derivatives of hematoporphyrin: A review Porphyrin Localization and Treatment was applied on tumor-bearing porphyrin-treated mice to study the.

Download PDF: Sorry, we are unable to provide the full text but you may find it at the following location(s): g (external link)Author: E.J. Land. Title(s): Porphyrin localization and treatment of tumors: proceedings of the Clayton Foundation International Symposium on Porphyrin Localization and Treatment of Tumors, Santa Barbara, California, April/ editors, Daniel R.

Doiron, Charles J. Gomer. Country of Publication: United States Publisher: New York: Liss, c We have synthesized two water soluble dendritic porphyrins, termed DP1 and DP2 and have successfully radiolabeled them with 99m Tc. These 99m Tc-labeled porphyrins were administered to C 6-glioma tumor bearing Wistar rats and scintiimaging and biodistribution studies were carried to muscle ratios of DP1 and DP2 were andby:.

Doiron D R Porphyrin Localization and Treatment of Tumors ed D R Doiron and C J Gomer (New York: Liss) pp Dorion D R, Svaasand L O and Profio A E Porphyrin Photosensitization ed D Kessel and T J Dougherty (New York: Plenum) pp Cited by: In the last decade, two porphyrin derivatives were approved in the U.S.A.

and in several other countries for the photodynamic treatment of various lesions. An overview of the different mechanisms for preferential porphyrinoid localization in malignant tumors is presented by: The use of tumor-avid porphyrins in delivering the desired MR imaging agent to tumor has been investigated by a independent studies of Hoffman et al.

and Pandey and co-workers. Among these conjugates, gadolinium-based porphyrin contrast media, particularly gadoporphyrin-2 has been extensively studies and found to be necrosis-avid. Cited by: